Using Riamet/Coartem


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Using Coartem ^®/Riamet^®

For details of clinical studies supporting the following information, please see Coartem ^®/Riamet^® Studies.
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Coartem^®/Riamet^® is indicated for the treatment of acute uncomplicated P. falciparum infections or mixed infections including P. falciparum.

The two brands, Coartem^® and Riamet^® are intended to address different medical needs in different countries.

Coartem^® is available in malaria-endemic countries. (See the list of countries where Coartem^® is authorised)

It is for the treatment, including emergency standby treatment, of malaria infections in endemic areas where the parasites may be resistant to other antimalarials.
Coartem^® dosage schedule - a 6-dose regimen is recommended for Coartem^®

Riamet^® is available in countries free of malaria. (See the list of countries where Riamet^® is authorised)

It is for the treatment of infected travellers returning from endemic areas.
In some countries it can be used as standby emergency treatment (self-medication) by non-immune travellers going to endemic areas who are unable to obtain medical care within 24 hours of suspected malaria symptoms

Riamet^® dosage schedule - a 6-dose regimen is recommended for Riamet^®.

Coartem^®/Riamet^®is not indicated for prophylaxis, or for treating severe malaria, including cerebral malaria, pulmonary oedema, or renal failure.

Coartem^®/Riamet^®is not indicated for, or been evaluated in, the treatment of malaria due to P. vivax, P. malariae or P. ovale. Coartem^®/Riamet^®is active against blood stages of Plasmodium vivax, but is not active against hypnozoites and therefore, an 8-amino-quinoline derivative such as primaquine must be given sequentially afterwards in cases of mixed infections of P. falciparum and P. vivax.

Coartem^®/Riamet^®is an oral formulation. Each light yellow uncoated tablet contains a fixed combination of artemether and lumefantrine in a 1:6 ratio.

	artemether 20mg
	lumefantrine 120mg